Takashi Takahashi
Yokohama University of Pharmacy, Japan
Title: New Synthetic Technology in Drug Discovery
Biography
Biography: Takashi Takahashi
Abstract
Automated synthesis and flow chemistry have attracted a great deal of attention in recent years because these process improve both the reproducibility and reliability of synthesis.1 Development of automated synthetic procedures and storage of relevant digital data allow anyone to reproduce the same results anytime and anywhere using the same apparatus and reagents. As a result, synthetic chemists can spend more time on advanced and challenging problems. Automated synthesis and flow chemistry often enhance the safety profile of the synthetic processes.2 Flow chemistry is effective for the hazardous reactions using toxic reagents or high pressure gases. Herein, we report the automated synthesis of taxol3, enediyne4, lewisX5and ketopiperazine analogues and the flow synthesis of peptides6 and aliphatic aldehydes7.